L. N. Romanchuk, V. M. Pyrochkin, Y. I. Karpovich, E. V. Chalaya, A. L. Belyaeva, Y. L. Karpovich, А.А. Shchetko
The article describes the clinical case of the Henoch-Schönlein disease in a patient of 53 years as an example of the relevance of the anamnestic data careful analysis, objective examination of the patient and the differential diagnosis for early detection. Polymorphism of cutaneous manifestations and visceral lesions can cause difficulties in the diagnosis of allergic purpura. Early administration of pathogenetically justified combined treatment leads to stabilization of the inflammatory process, avoidance of possible destruction of the internal organs as well as development of complications and relapses.
keywords: allergic purpura, anticoagulants, Henoch-Schönlein disease, disaggregant glucocorticoid therapy, hemorrhagic vasculitis, immune complexes, microthrombogenesis

for references: L. N. Romanchuk, V. M. Pyrochkin, Y. I. Karpovich, E. V. Chalaya, A. L. Belyaeva, Y. L. Karpovich, А. А. Shchetko. Allergic Purpura in the Therapeutic Practice. Neotlozhnaya kardiologiya i kardioovaskulyarnye riski [Emergency cardiology and cardiovascular risks], 2019, vol. 3, no. 2, pp. 747–750

1. Klinicheskiy protokol diagnostiki i lecheniya pacientov (vzrosloe naselenie) s revmaticheskimi zabolevaniyami pri okazanii medicinskoy pomosch’i v ambulatorny’h i stacionarny’h usloviyah rayonny’h, oblastny’h i respublikanskih organizaciy zdravoohraneniya : pril. k prikazu M-va zdravoohraneniya Resp. Belarus’, 10 maya 2012 g., № 52 [electronic resource] [Clinical Protocol of diagnosis and treatment of patients (adults) with rheumatic diseases in the provision of medical care in outpatient and inpatient conditions of district, regional and national health organizations: ADJ. to the order of M-va Rep. Belarus, 10 May 2012 g, № 522]. Available at: http://minzdrav.gov.by/ru/dlya-spetsialistov/standarty-obsledovaniyai-lecheniya/2012-god.php. (accessed 28.09.2019). (in Russian).
2. Kozare zova T.I., Klimkovich N.N., Kuvshinnikov V.A., Kozare zov S.N. Gemorragicheskiy vaskulit u detey : ucheb-metod. posobie [Hemorrhagic vasculitis in children: study method. benefit]. Minsk, BelMAPO, 2007, S. 39. (in Russian).
3. Krivosheev O.G., Gulyaev S.V., Semenovy’h A.G. K voprosu o patogeneze purpury’ SHenleyna-Genoha [The pathogenesis of purpura Henoch-Schonlein purpura]. Vrach, 2005, no. 5, pp. 34–36. (in Russian).
4. Mercalova I.B. Vaskulity’ koji [Vasculitis of the skin]. Lechasch’iy vrach, 2011, no. 5, pp. 35–37. (in Russian).
5. Skvorcov V.V., Tumarenko A.V. Problemy’ diagnostiki i lecheniya tyajelogo gemorragicheskogo vaskulita [Problems of diagnosis and treatment of severe hemorrhagic vasculitis]. Med alfavit, 2013, vol. 2, no. 13, pp. 28–31. (in Russian).
6. Kellerman P.S. Henoch-Schönle(inpurpura in adults. Am J Kidney Dis, 2006, vol. 48, no. 6, pp. 1009–1016.
7. Saulsbury F.T. Clinical update: Henoch-Schönleinpurpura. Lancet, 2007, vol. 369, pp. 976–978.
8. Weiss P.F., Feinstein J.A., Luan X., Burnham J.M., Feudtner C. Effects of corticosteroid on Henoch-Schönleinpurpura: a systematic review. Pediatrics, 2007, vol. 120, no. 6, pp. 1079–1087.
9. Muhin N.A., Gulyaev, S.V., Krivosheev O.G., Semenkova E.N., Kogan E.A., Ohotnikova N.L., Zavodnov V.YA., Gmoshinskiy I.V., Mazo V.K., Kreyn R., B’yarnason I. Klinicheskoe i ppognosticheskoe znachenie porajeniya jeludochno-kishechnogo trakta pri sistemny’h sosudisty’h puppupah [Clinical and prognostic significance of gastrointestinal tract lesions in systemic vascular purpura]. Terapevt arh, 2003, vol. 75, no. 2, pp. 50–54. (in Russian).
10. Pyne D., Mootoo R., Bhanji A. Colchicine for the treatment of recurrent Henoch-Schonleinpurpura in an adult. Rheumatology (Oxford), 2001, vol. 40, no. 12, pp. 1430–1431.
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