T.V. Amvrosieva, N.P. Mitkovskaya, Z.F. Bohush, A.S. Arinovich, E.M. Balysh
The article describes the algorithm of virological examination of patients with clinically suspected viral myocarditis and presents the results of its use in a group of 49 patients with respect to 12 causative agents of viral infections - cytomegalovirus, Epstein-Barr virus, varicella-zoster virus, human herpes virus type 6, herpes viruses types 1 and 2, enteroviruses, parvovirus B 19, hepatitis C virus, influenza A and B viruses, rhinoviruses and adenoviruses. The presence of serological markers of viral infections (antiviral IgM) was detected in 42.1% of patients, the genetic material of pathogens (RNA / DNA) in the blood serum in 16.0% of patients, in heart tissues – in 75.0%. Among the viral pathogens revealed in the biological material, adenoviruses, parvovirus B 19, and human herpes virus type 6 dominated. According to serodiagnosis IgM to enteroviruses was most often detected in blood serum.
keywords: clinically suspected myocarditis, viral infections, immune-enzyme assay, polymerase chain reaction

for references: T.V. Amvrosieva, N.P. Mitkovskaya, Z.F. Bohush, A.S. Arinovich, E.M. Balysh. The causative agents of viral myocarditis. Neotlozhnaya kardiologiya i kardiovaskulyarnye riski [Emergency cardiology and cardiovascular risks], 2020, vol. 4, no. 1, pp. 817–823

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